Results 231 to 240 of about 2,951,060 (291)

Induction of cytochrome P450 2C9 and P‐glycoprotein activity by antiseizure medications: A systematic review and network meta‐analysis

open access: yesEpileptic Disorders, EarlyView.
Abstract Objectives Antiseizure medications (ASMs) can induce the activity of drug‐metabolizing enzymes and drug transporters, including cytochrome P450 (CYP)2C9 and P‐glycoprotein (P‐gp). Our objective was to comparatively assess the effects of ASMs on exposure to clinical CYP2C9 and P‐gp substrates.
Hagar Cohen   +4 more
wiley   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara   +7 more
wiley   +1 more source

Bacterial fecal microbiome composition associated with HIV stage among rural and peri-urban adults living with HIV in Uganda. [PDF]

open access: yesBMC Infect Dis
Morawski BM   +7 more
europepmc   +1 more source

Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

open access: yesEpilepsia, EarlyView.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer   +12 more
wiley   +1 more source

Effects of Day‐Patient Treatment on Eating Disorder Symptoms in Persons With Bulimia Nervosa: A Meta‐Analysis

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Outpatient treatment for bulimia nervosa (BN) often fails to reduce core symptoms like binge eating and purging, while inpatient care is costly and separates patients from their everyday environment. Day‐patient treatment offers a middle ground by providing intensive daytime therapy with the opportunity to apply skills at home.
Anna L. Dieffenbacher   +2 more
wiley   +1 more source

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