Results 51 to 60 of about 4,610 (303)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Gender and circadian differences of effectiveness of diazepam on stressed rats in the «open field»

open access: yesНаука. Инновации. Технологии, 2022
Sexual dissimilation of motor and emotional responses in stressed and stressed-free rats after administered of diazepam in doses 0,1 and 0,5 mg / kg during the circadian cycle in the «open field» shows.
Eleonora Aslibekovna Manveljan   +2 more
doaj  

Pentatoma dissimile

open access: yes, 2010
Pentatoma dissimile = Palomena prasina (Linnaeus, 1761). Green label: “ Pentatoma dissimile, haud diversum, D. Deyrolles, Brasilia”. Remarks. This specimen is conspecific with other four of the same box collected in Italy. Although the original label indicates the Neotropical Region, P. prasina is in fact a Palearctic species. Box 16 (16-17).
Grazia, Jocélia, Campos, Luiz A.
openaire   +2 more sources

Protapion dissimile

open access: yes, 2020
Published as part of Ghahari, Hassan & Colonnelli, Enzo, 2020, An annotated checklist of the Iranian Brentidae (Coleoptera: Curculionoidea), pp.
Ghahari, Hassan, Colonnelli, Enzo
openaire   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

A phonetico-semantic analysis of verb-noun contractions in Yoruba

open access: yesStudies in African Linguistics, 1986
This paper highlights the various studies which have been carried out to determine the rules which govern the elision of one of the vowels in a verb-noun concatenation where the verb is vowel-final and the noun vowel-initial.
B. Rotimi Badejo
doaj   +3 more sources

Repair strategies in labial dissimilation: diminutive formations in Xitsonga

open access: yesStellenbosch Papers in Linguistics Plus, 2014
This paper presents phonological processes in Xitsonga diminutives. The round vowels /u/ and /o/ are changed into the glide [w] to avoid vowel hiatus.
Lee, Seunghun J., Burheni, Clementinah
doaj   +1 more source

In silico and in vivo analyses reveal key metabolic pathways enabling the fermentative utilization of glycerol in Escherichia coli

open access: yesMicrobial Biotechnology, 2022
Summary Most microorganisms can metabolize glycerol when external electron acceptors are available (i.e. under respiratory conditions). However, few can do so under fermentative conditions owing to the unique redox constraints imposed by the high degree ...
James M. Clomburg   +2 more
doaj   +1 more source

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