Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk +6 more
wiley +1 more source
Energetics of Formation and Fragmentation of Carbon-Centered Radicals α- to Nitrogen and Oxygen in <i>N</i>,<i>N</i>,<i>O</i>‑Trimethylhydroxylamine in Comparison to Trimethylamine and Dimethyl Ether: Implications for Medicinal and Synthetic Chemistry. [PDF]
Givhan RH, Schaefer HF, Crich D.
europepmc +1 more source
Magnetoactive Hydrogels to Probe Curvature‐Directed Endothelial Cell Mechanosensing
This work establishes a platform to investigate local curvature as a regulator of endothelial mechanosensing independent of shear stress. Magnetoactive hydrogels enable on‐demand curvature of endothelial monolayers to reproduce tortuosity quantified by clinically established metrics.
Avinava Roy +6 more
wiley +1 more source
Hydraplexing: Design Principles for Fragment-Level Signal Amplification Using a Multi-Amine Model Analyte. [PDF]
Li A, Ayon NJ, Nemes P.
europepmc +1 more source
Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms
Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet +11 more
wiley +1 more source
Ferroelectric Quantum Dots for Retinomorphic In‐Sensor Computing
This work has provided a protocol for fabricating retinomorphic phototransistors by integrating ferroelectric ligands with quantum dots. The resulting device combines ferroelectricity, optical responsiveness, and low‐power operation to enable adaptive signal amplification and high recognition accuracy under low‐light conditions, while supporting ...
Tingyu Long +26 more
wiley +1 more source
Assessment of the variational quantum eigensolver (VQE) for bond dissociation of H 2 , H 3 + , and CH 5 +. [PDF]
Marques de Lima A +3 more
europepmc +1 more source
Energetic Offset in Organic Solar Cells‐ Importance, Confusion and Outlook
Energetic offsets in organic solar cells (OSCs) remain a subject of debate due to measurement‐ and lab‐dependent discrepancies. This Perspective clarifies the physical origins of these variations and identifies temperature‐dependent electro‐optical methods as a reliable approach to obtain consistent offset values.
Nakul Jain +5 more
wiley +1 more source
Advances in catalytic hydrogen storage materials: progress, breakthroughs, and challenges toward scalable applications. [PDF]
Shulin P, Tahri W, Khan R, Alshaaer M.
europepmc +1 more source
Single‐Chromophore Homojunction Organic Solar Cells: A Path to Simplicity and Efficiency
This perspective discusses how the intrinsic optoelectronic properties of organic semiconductors, their molecular packing in the solid‐state, and internal energetic gradients within a device can enable free‐charge carrier generation in homojunction organic solar cells.
Shaun McAnally +2 more
wiley +1 more source

