Results 231 to 240 of about 18,428 (291)

Clinical Heterogeneity of Major Depressive Disorder: The Role of Trauma, Dissociation, and Sleep. [PDF]

J Clin Med
Namlı Z, Tamam L, Demirkol ME, Karaytuğ MO, Yeşiloğlu C, Çetin Demirtaş S, Uğur K.   +6 more
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Pornographic consumption in young adult men and its relationship with stress and dissociative symptoms: A cross-sectional STROBE design. [PDF]

Medicine (Baltimore)
Privara M, Bob P.
europepmc   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Rapid reduction of suicidal ideation with transient dissociative and "drunken gait" symptoms after intranasal esketamine, with music intervention: a case report. [PDF]

Front Psychiatry
Tian H, Zhang Z, He Y, Su Y, Zhu X, Ding Y, Yu H, Jin L, Liu J.   +8 more
europepmc   +1 more source

Scaling injustice: epistemic harm in DID and what clinical records will teach AI. [PDF]

Front Psychiatry
Akinlade O.
europepmc   +1 more source

Dissociative Bipolar At-Risk Phenotype: Traumatic Burden and Subthreshold Affective Psychopathology in a Help-Seeking Youth Sample. [PDF]

Brain Sci
Scopetta F, Barbi M, Cinesi G, De Giorgi F, Tortorella A, Menculini G.   +5 more
europepmc   +1 more source

Relationship between emotional competence, dissociative symptoms and borderline personality disorder traits in female adolescents engaging in non-suicidal self-injury. [PDF]

Child Adolesc Psychiatry Ment Health
Otto A, Jacob R, Jarvers I, Kandsperger S, Brunner R.   +4 more
europepmc   +1 more source

Emotion dysregulation and dissociation mediate the association between alexithymia and depressive symptoms in individuals with alcohol use disorder. [PDF]

Alcohol Alcohol
Zaorska J, Kopera M, Rydzewska M, Suszek H, Kobyliński P, Trucco EM, Jakubczyk A.   +6 more
europepmc   +1 more source

Longitudinal Management of Post-traumatic Brain Injury Bipolar-Spectrum Disorder With Low-Dose Oral Glutamatergic Augmentation: Extended Follow-Up Revealing Induction, Overshoot, Stabilization, and Transition to PRN Maintenance. [PDF]

Cureus
Cheung N.
europepmc   +1 more source