Results 101 to 110 of about 11,632,967 (345)
, 2013 The objective of the present work was to enhance the solubility and dissolution rate of the drug raloxifene HCl (RLX), which is poorly soluble in water.
P. Patil +3 more
semanticscholar +1 more source
Sensitivity of dissolution rate to location in the paddle dissolution apparatus
Journal of Pharmacy and Pharmacology, 2002 Abstract The aim of the present study was to determine the apparent diffusion boundary layer and dissolution rate constant for various surfaces of compacts and at various locations in the USP paddle dissolution apparatus. Benzoic acid compacts were coated with paraffin wax leaving only the surface under investigation free for dissolution.
A M, Healy +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Mixing across fluid interfaces compressed by convective flow in porous media
, 2017 We study the mixing in the presence of convective flow in a porous medium. Convection is characterized by the formation of vortices and stagnation points, where the fluid interface is stretched and compressed enhancing mixing.
Dentz, Marco, Hidalgo, Juan J.
core +1 more source
Bio resorbability of the modified hydroxyapatite in Tris-HCL buffer [PDF]
, 2016 The solubility of carbonated hydroxyapatite powders and granulated carbonated hydroxyapatite produced from the synovial biofluid model solution has been studied. The kinetic characteristics of dissolution were determined. It was found that the solubility
Golovanova, O. A. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Influence of process variables on the properties of simvastatin self-emulsifying granules obtained through high shear wet granulation [PDF]
, 2015 Improvements of the oral bioavailability of lipophilic drugs can be obtained using lipidic formulations such as the self-emulsifying drug delivery systems.
Benda L. +5 more
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Catalysis and chemical mechanisms of calcite dissolution in seawater [PDF]
, 2017 Near-equilibrium calcite dissolution in seawater contributes significantly to the regulation of atmospheric CO_2 on 1,000-y timescales. Despite many studies on far-from-equilibrium dissolution, little is known about the detailed mechanisms responsible ...
Adkins, Jess F. +5 more
core +2 more sources
International Journal of Nanomedicine, 2012 In this paper work, four naked nanocrystals (size range 80–700 nm) were prepared without any surfactant or polymer using the solvent/nonsolvent method.
Jiao Sun +6 more
semanticscholar +1 more source