Results 311 to 320 of about 555,478 (356)

Dissolution Modeling: Factors Affecting the Dissolution Rates of Polydisperse Powders

Pharmaceutical Research, 1993
The dissolution rates of two lots of hydrocortisone (fine and coarse) were simulated using a computer program based on a Noyes-Whitney-type equation. Derivations of the equation were made to compare the accuracy of simulations using spherical and cylindrical particle geometry, with and without a time-dependent diffusion layer thickness.
A T, Lu, M E, Frisella, K C, Johnson
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Dissolution Rate Studies on Methylprednisolone Polymorphs

Journal of Pharmaceutical Sciences, 1964
Dissolution rates (DR) of methylprednisolone polymorphs I and II were determined by the rotating disk method as a function of rate of rotation (RR). The results show that the DR-RR relationship differs from that normally expected in the case of diffusion-controlled dissolution from rotating disks.
G, LEVY, J A, PROCKNAL
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Alunite dissolution rates: Dissolution mechanisms and implications for Mars

Geochimica et Cosmochimica Acta, 2016
Abstract Alunite (KAl 3 (SO 4 ) 2 (OH) 6 ) is a hydrated aluminous sulfate mineral associated with acidic, oxidizing aqueous environments on Earth. Additionally, orbiting spacecraft and rovers on Mars have reported spectral data that indicate a range of mono- and polyhydrated sulfate phases and hydroxysulfate phases, suggesting such conditions also ...
J.L. Miller, A.S. Elwood Madden, C.M. Phillips-Lander, B.N. Pritchett, M.E. Elwood Madden   +4 more
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Dissolution Rate of Cholesterol in Monooctanoin

Hepatology, 1984
Monooctanoin is used clinically for dissolution of common bile duct cholesterol gallstones. A number of factors influencing the dissolution rate of cholesterol monohydrate in this solvent were investigated. Water increased cholesterol dissolution rate in a manner inconsistent with previous solubility measurements.
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The dissolution rate of zinc pyrithione

International Journal of Cosmetic Science, 1985
SynopsisA method of measuring and correlating the rate at which zinc pyrithione dissolves during a shampoo is described. The rise in zinc concentration of a solution in a stirred vessel following the introduction of a dose of zine pyrithione suspension was measured as a function of time using atomic absorption spectrophotometry. An analysis of the mass
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Variation of Crystal Dissolution Rate Based on a Dissolution Stepwave Model

Science, 2001
A formulation based on defect-generated dissolution stepwaves of the variation of dissolution rate with the degree of undersaturation is validated by near-atomic-scale observations of surfaces, Monte Carlo simulations, and experimental bulk dissolution rates.
A C, Lasaga, A, Luttge
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Investigation of dissolution kinetics for high rates of dissolution

Soviet Physics Journal, 1970
A procedure was developed for investigating the dissolution of crystals that rub against a substrate with the solvent, whereby the process becomes significantly intensified. A theory of the method is presented. The kinetics of dissolution of azobenzene in alcohol at different rates of substrate motion, normal loads on the crystal, and temperatures is ...
N. N. Nilova, G. M. Bartenev, V. T. Borisov   +2 more
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Hydrodynamic approach to dissolution rate

Pharmaceutisch weekblad, 1981
In the pharmaceutical literature the dissolution of solids in liquids is usually described using the stagnant layer model. This model, however, does not reflect the actual situation with respect to the hydrodynamics involved. This review analyses the different hydrodynamic situations in which dissolution may take place.
H. Grijseels, D. J. A. Crommelin, C. J. de Blaey   +2 more
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Dissolution Rates of Surfactants

2008
Information on dissolution rates of surfactants is reviewed and discussed. One or more viscous liquidcrystalline phases form during dissolution in water of pure liquid nonionic surfactants of the linear alcoholethoxylate type, as expected from known equilibrium phase diagrams.
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Dissolution specifications based on release rates

Journal of Pharmaceutical Sciences, 1999
A procedure based on release rates is proposed for the establishment of dissolution specifications that ensure the bioequivalence of a test and a reference product. This procedure, which confines Cmax (the maximum concentration of the drug in vivo) and AUCinfinity (the area under the time-concentration curve, extrapolated to infinity) values within any
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