Results 241 to 250 of about 1,243,090 (307)

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

CT-guided three-dimensional reconstruction with predictive modeling for personalized esophageal anastomosis in type C esophageal atresia. [PDF]

Front Surg
Lozovoy V, Sakuov Z, Yerekeshov A, Rustemov D, Bilal R, Zhangaskanov T, Shatkenova Z.   +6 more
europepmc   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Klotho Deficiency Impairs Distal Potassium Homeostasis Through mTORC1-Dependent Suppression of ROMK. [PDF]

Acta Physiol (Oxf)
Kawarazaki W, Ayuzawa N, Nishimoto M, Hirohama D, Ueda K, Marumo T, Fujita T.   +6 more
europepmc   +1 more source

Acute Limb Ischemia Caused by Distal Embolization from an External Iliac Artery Pseudoaneurysm Associated with a Protruding Acetabular Screw: A Case Report. [PDF]

Vasc Specialist Int
Tada Y, Kikuchi S, Yuzawa S, Tanino M, Mitsutake R, Azuma N.   +5 more
europepmc   +1 more source

Pelvic and hindlimb osteology and ontogeny of a troodontid from the upper member of the Two Medicine Formation (Cretaceous) of Montana. [PDF]

PLoS One
Varricchio DJ, Caldwell HR.
europepmc   +1 more source

Mesial-Distal Patterns of Alveolar Bone Loss in Periodontitis and Peri-Implantitis: A Comparative Radiographic Study. [PDF]

Dent J (Basel)
Grammatikis E, Ștefănescu CL, Sachelarie L, Popa MF, Radu MD, Murineanu RM, Șapte E.   +6 more
europepmc   +1 more source

Cryo-EM Structure of Siphophage Avs-1 Reveals a Conserved Virion Architecture with a Specialized Tripod-like Tail Tip for Host Recognition. [PDF]

Viruses
Liu J, Li C, Yang X, Yang F, Liu H.
europepmc   +1 more source