This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou +12 more
wiley +1 more source
Intermittent fasting alleviates irradiation-induced neuronal mitochondrial damage in mice. [PDF]
Li Y, Fan X, Pei Y, Wu K.
europepmc +1 more source
Fluoride varnish application and the temporal evolution of supragingival microbiota in children with differential caries risk. [PDF]
Liu F +9 more
europepmc +1 more source
Effects of table tennis on vision in children and adolescents: a multilevel dose-response meta-analysis. [PDF]
Jin X, Wang Y, Guo J, Cao A.
europepmc +1 more source
Binocular Reading Speed Comparison: Patients After Bilateral Trifocal IOL Implantation versus Those without Cataract -A Prospective, Dual-Center Study. [PDF]
Lin Y +7 more
europepmc +1 more source
Maritime traffic congestion identification and ship trajectory prediction using temporal graph convolutional networks. [PDF]
Zhou W, Zhang W, Sun S, Zhang Y.
europepmc +1 more source
An adaptive A-Star algorithm to handle blood transportation using UAVs. [PDF]
Zaki C +6 more
europepmc +1 more source
An inequality involving the second largest and smallest eigenvalue of a distance-regular graph [PDF]
For a distance-regular graph with second largest eigenvalue (resp., smallest eigenvalue) θ1 (resp., θD) we show that (θ1+1)(θD+1)⩽-b1 holds, where equality only holds when the diameter equals two.
Jack H Koolen, Jongyook Park
exaly +4 more sources

