Results 51 to 60 of about 28,279 (264)
Shortest Paths in Distance-regular Graphs
European Journal of Combinatorics, 2000 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Enrique Bendito +2 more
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Distance equienergetic graphs of diameter 4
Examples and CounterexamplesLet Γ1, Γ2 and Γ3 be graphs with pairwise disjoint vertex sets. The graph Θ(Γ1,Γ2,Γ3) is obtained from the graphs Γ1∘Γ3 (the corona product) and Γ2 by joining each vertices of Γ1 in Γ1∘Γ3 with every vertices in Γ2.
B.J. Manjunatha +2 more
doaj +1 more source
Locally Pseudo-Distance-Regular Graphs
Journal of Combinatorial Theory, Series B, 1996 The concept of local pseudo-distance-regularity, introduced in this paper, can be thought of as a natural generalization of distance-regularity for non-regular graphs. Intuitively speaking, such a concept is related to the regularity of graph \(\Gamma\) when it is seen from a given vertex.
Miguel Angel Fiol +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Distance-Locally Disconnected Graphs
Discussiones Mathematicae Graph Theory, 2013 For an integer k ≥ 1, we say that a (finite simple undirected) graph G is k-distance-locally disconnected, or simply k-locally disconnected if, for any x ∈ V (G), the set of vertices at distance at least 1 and at most k from x induces in G a disconnected
Miller Mirka +2 more
doaj +1 more source
Electronic Journal of Graph Theory and Applications, 2015 We study a family of graphs related to the $n$-cube. The middle cube graph of parameter k is the subgraph of $Q_{2k-1}$ induced by the set of vertices whose binary representation has either $k-1$ or $k$ number of ones.
C. Dalfo, M. A. Fiol, M. Mitjana
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Distance-regular antipodai covering graphs
Journal of Combinatorial Theory, Series B, 1988 Let G be a regular graph with diameter d. G is said to be antipodal if given any distinct vertices u, v, w of G with v and w at distance d from u, then v is distance d from w. G is called distance-regular if for vertices u, v, in G of distance i apart, v is adjacent to \(c_ i\) vertices distance i-1 from u, \(a_ i\) vertices distance i from u, and \(b_
Robert E. L. Aldred, Chris D. Godsil
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source