Results 51 to 60 of about 118,378,802 (306)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The distance Seidel matrix of connected graphs
AKCE International Journal of Graphs and CombinatoricsFor a connected graph G, we present the concept of a new graph matrix related to its distance and Seidel matrix, called distance Seidel matrix [Formula: see text]. Suppose that the eigenvalues of [Formula: see text] be [Formula: see text] In this article,
T. Haritha, A. V. Chithra
doaj +1 more source
Graphs and CombinatoricsAbstract In 1971, Graham and Pollak provided a formula for the determinant of the distance matrix of any tree on n vertices. Yan and Yeh reproved this by exploiting the fact that pendant vertices can be deleted from trees without changing the remaining entries of the distance matrix.
Joshua N. Cooper, Gabrielle Tauscheck
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Distance independence in graphs
Discussiones Mathematicae Graph Theory, 2011 For a set D of positive integers, we define a vertex set SV (G) to be D-independent if u,v 2 S implies the distance d(u,v) 㘲 D. The D-independence numberD(G) is the maximum cardinality of a D-independent set. In particular, the independence number (G) = {1}(G).
J. Louis Sewell, Peter J. Slater
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
IEEE Access, 2018 The resistance distance is widely used in random walk, electronic engineering, and complex networks. One of the main topics in the study of the resistance distance is the computation problem.
Qun Liu, Jia-Bao Liu, Shaohui Wang
doaj +1 more source
The Electronic Journal of Combinatorics, 2016 This is a survey of distance-regular graphs. We present an introduction to distance-regular graphs for the reader who is unfamiliar with the subject, and then give an overview of some developments in the area of distance-regular graphs since the monograph 'BCN' [Brouwer, A.E., Cohen, A.M., Neumaier, A., Distance-Regular Graphs, Springer-Verlag, Berlin,
Edwin R. van Dam +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Discrete Applied Mathematics, 2012 Accepted for publication in Discrete Applied Mathematics.
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source