Results 71 to 80 of about 114,426,441 (303)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

An Odd Characterization of the Generalized Odd Graphs [PDF]

open access: yes
2010 Mathematics Subject Classification: 05E30, 05C50;distance-regular graphs;generalized odd graphs;odd-girth;spectra of graphs;spectral excess theorem;spectral ...
Dam, E.R. van, Haemers, W.H.
core   +2 more sources

On the distance eigenvalues of Cayley graphs

open access: yesپژوهش‌های ریاضی, 2022
In this paper, graphs are undirected and loop-free and groups are finite. By Cn, Kn and Km,n we mean the cycle graph with n vertices, the complete graph with n vertices and the complete bipartite graph with parts size m and n, respectively.
Majid Arezoomand
doaj  

The relationship between the intrinsic Čech and persistence distortion distances for metric graphs

open access: yesJournal of Computational Geometry, 2019
Metric graphs are meaningful objects for modeling complex structures that arise in many real-world applications, such as road networks, river systems, earthquake faults, blood vessels, and filamentary structures in galaxies.
Ellen Gasparovic   +6 more
doaj   +1 more source

Distance-hereditary graphs

open access: yesJournal of Combinatorial Theory, Series B, 1986
A distance-hereditary graph is a connected graph in which every induced path is isometric, that is, the distance between any two vertices in an induced path equals their distance in the graph. A block graph is a conncted graph in which every block (i.e., maximal 2-connected subgraph) is complete. Let G be a graph with distance function d.
Hans-Jürgen Bandelt   +1 more
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

On Wiener index of graph complements [PDF]

open access: yesTransactions on Combinatorics, 2014
Let $G$ be an $(n,m)$-graph. We say that $G$ has property $(ast)$ if for every pair of its adjacent vertices $x$ and $y$, there exists a vertex $z$, such that $z$ is not adjacent to either $x$ or $y$.
Jaisankar Senbagamalar   +2 more
doaj  

On distance-balanced graphs

open access: yesEuropean Journal of Combinatorics, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Aleksandar Ilic   +2 more
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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