Results 51 to 60 of about 2,194,803 (325)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Classified AGV Material Flow and Layout Data Set for Multidisciplinary Investigation
IEEE Access, 2023 Automated Guided Vehicles (AGV) are increasingly used in industry to automate material flow tasks. To efficiently operate systems of AGVs, researchers have proposed many different planning and control methods, e.g., for scheduling, dispatching, and ...
Marvin Sperling +4 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Современные информационные технологии и IT-образование, 2019 Bioinformatics has two important problems for the study of evolutionary processes: calculating the distance between DNA sequences and restoring a matrix of distances sequences of different genomes when not all initial elements are known. Due to the large
Mikhail E. Abramyan +2 more
doaj +1 more source
Factoring distance matrix polynomials
Discrete Mathematics, 1993 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
On the Distance Spectral Radius of Trees with Given Degree Sequence
Discussiones Mathematicae Graph Theory, 2020 We consider the problem of maximizing the distance spectral radius and a slight generalization thereof among all trees with some prescribed degree sequence.
Dadedzi Kenneth +2 more
doaj +1 more source
Research on decision method based on probability hesitation fuzzy comprehensive distance measure
Xibei Gongye Daxue Xuebao, 2023 Aiming at the defects of the existing probabilistic hesitation fuzzy distance measures, which require the number of membership degree to be consistent and the order to be rearranged, a probabilistic hesitation fuzzy multi-attribute decision making method
LIU Ying, GUAN Xin, WU Bin
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source