Results 151 to 160 of about 5,192,383 (306)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

A Community College Distance Education Delivery Model for a Post Diploma/Degree Human Services Management Certificate Program

open access: yes, 2008
From 2005 to 2006, the Community Studies Department Chair at Algonquin College approached relevant program advisory committees with the intention of developing a post diploma/degree certificate program in the area of front line human services management.
Sauve, J.
core  

Subcellular Euclidean distance measurements with multicolor fluorescence localization imaging in cultured cells. [PDF]

open access: yesSTAR Protoc, 2021
Germanova TE   +4 more
europepmc   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Course/Materials Development for Distance Education: Additional Readings and Exercises

open access: yes
Note: No date of issue was indicatedThis contains Course/Materials Development for Distance Education sessions on the following topics: (1.) Part 1 - Planning materials development: where do we begin, Part 2 -The target audience: profiling your learners,
The Distance Education Center of The University of the West Indies and The International Extension College
core  

Long Distance Runners

open access: yes, 2013
ColourLong Distance ...

core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

A Non Conventional Unit Distance Code for Optical Rotary Encoder Applications

open access: yes, 2001
This paper presents a unit distance code for absolute optical rotary encoders which relaxes the geometrical constraints set by the conventional Gray code to the minimum allowed value of the code disk radius.
LIBERALI, VALENTINO   +7 more
core  

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