Results 61 to 70 of about 1,644,928 (302)

Only distances are required to reconstruct submanifolds [PDF]

, 2017
In this paper, we give the first algorithm that outputs a faithful reconstruction of a submanifold of Euclidean space without maintaining or even constructing complicated data structures such as Voronoi diagrams or Delaunay complexes.
Boissonnat, Jean-Daniel, Dyer, Ramsay, Ghosh, Arijit, Oudot, Steve Y.   +3 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The Applicability of Traditional Protection Methods to Lines Emanating from VSC-HVDC Interconnectors and a Novel Protection Principle

Energies, 2016
Voltage source converter (VSC)-based high voltage direct current (VSC-HVDC) interconnectors can realize accurate and fast control of power transmission among AC networks, and provide emergency power support for AC networks. VSC-HVDC interconnectors bring
Shimin Xue, Jingyue Yang, Yanxia Chen, Cunping Wang, Zhe Shi, Miao Cui, Botong Li   +6 more
doaj   +1 more source

Effect of cross-country fault of distance protection in transmission line with different voltage levels [PDF]

, 2014
Transmission overhead line is one of the main elements in electric power system. Electrical power system comprises of generation, transmission and distribution. For transmission lines, it is used to transmit electric power to large load center. Nowadays,
Abdul Karim, Sazali P., Habi Buddin, Mohd. Hafiz, Mohd. Yusof, Alias, Mohd. Zin, Abdullah Asuhaimi, Omar, Nur Afifah   +4 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Geometry of Distance Protection

Distance relays detect faults on transmission lines. They face uncertainty from the fault's location and resistance, as well as the current from the line's remote terminal. In this paper, we aggregate this uncertainty with the Minkowski sum. This allows us to explicitly model the power grid surrounding the relay's line, and in turn accommodate any mix ...
Taylor, Josh A., Domínguez-García, Alejandro D.   +1 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Large-scale quantum networks based on graphs

, 2016
Society relies and depends increasingly on information exchange and communication. In the quantum world, security and privacy is a built-in feature for information processing.
Bruß, Dagmar, Epping, Michael, Kampermann, Hermann   +2 more
core   +1 more source