Results 151 to 160 of about 17,512,468 (321)

First density estimates of the Endangered Claire's mouse lemur Microcebus mamiratra and recommendations for its conservation

Oryx
Mouse lemurs Microcebus spp. are small, nocturnal primates endemic to Madagascar. The genus is extraordinarily diverse, with 25 extant species, several of which have been described recently.
Luke D. Martin, Herison Razafimanantsoa, Eva S. Nomenjanahary, Sylviane Volampeno, Alison M. Behie   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

On the Uniformly Most Powerful Invariant Test for the Shoulder Condition in Line Transect Sampling [PDF]

In wildlife population studies one of the main goals is estimating the population abundance. Line transect sampling is a well established methodology for this purpose.
Riccardo Borgoni, Piero Quatto
core  

Estimating waterfowl breeding pair and brood densities using distance sampling with uncrewed aerial systems

Ecological Solutions and Evidence
Wildlife management relies on effective methods to estimate population indices, which are crucial for understanding the status and trends of wildlife populations and the factors that influence their persistence.
Amanda E. Griswold, Benjamin S. Sedinger, Amy A. Shipley   +2 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

The Uniformly Most Powerful Invariant Test for the Shoulder Condition in Point Transect Sampling [PDF]

Estimating population abundance is of primary interest in wildlife population studies. Point transect sampling is a well established methodology for this purpose.
Riccardo Borgoni, Piero Quatto
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Sample, distance and analytical choices

, 2009
info:eu-repo/semantics ...
openaire   +4 more sources

Seven Year Decline of Mountain Hare Abundance in the Peak District, England

Ecology and Evolution
In England, the mountain hare is found only in the Peak District and is a remnant population surviving from translocations from Scotland during the 1870s of the genetically distinct subspecies Lepus timidus scoticus.
Carlos P. E. Bedson, Katherine Walsh, Humphrey Q. P. Crick   +2 more
doaj   +1 more source