Results 231 to 240 of about 343,079 (292)

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Effects of drop net and helicopter net-gun capture on movement, space use, and survival of white-tailed deer. [PDF]

PLoS One
Stewart DG, Beaver JT, Cooksey ML, Grantham C, Pierce BL, Lopez RR, Webb SL.   +6 more
europepmc   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Selection and transmission of the gut microbiome alone can shift mammalian behavior. [PDF]

Nat Commun
Suzuki TA, Tanja AS, Waters JL, Jakob D, Vu DL, Ballinger MA, Di Rienzi SC, Chang H, de Araujo IE, Tyakht AV, Ley RE.   +10 more
europepmc   +1 more source

Effect of protein-rich diet and the tamarind trypsin inhibitor on behavioral disorders in obese zebrafish. [PDF]

Front Nutr
Silva AKXG, Medeiros I, Mamede JP, Trajano AC, Costa TIDS, de Sousa ALM, de Souza LAL, Nascimento AMS, da Silva-Maia JK, Morais AHA.   +9 more
europepmc   +1 more source

Median Raphe projection into the dorsal dentate gyrus modulates anxiety behavior and coping with learning under stress. [PDF]

Sci Rep
Quan J, Kriebel M, Anunu R, Snippe-Strauss M, Volkmer H, Richter-Levin G.   +5 more
europepmc   +1 more source

Akkermansia muciniphila vesicles attenuate smoking-induced cognitive decline via ILA-mediated AhR-dependent microglial reprogramming. [PDF]

J Nanobiotechnology
Zhu B, Huang J, Zhang H, Lin H, Chen T, Min L, Yang Y, Liu Y, Guo S.   +8 more
europepmc   +1 more source