FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
A Rare Case of Hemoperitoneum Diagnosed with Point of Care Ultrasound (POCUS). [PDF]
POCUS JBai J, Cutler T.
europepmc +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
A concise guide of contemporary cardiovascular imaging practices to differentiate athlete's heart in the gray zone. [PDF]
Heart Fail RevPagourelias ED +7 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Improved meet-in-the-middle attack on Joltik-BC-128
网络与信息安全学报The Joltik-BC, adopting the substitution-permutation network structure and Tweakey framework, was a lightweight tweakable block cipher published at ASIACRPYPT 2014. By researching the internal characteristic of the Joltik-BC, a 6-round meet-in-the-middle
LI Zheng +3 more
doaj
Orthostatic hypotension in a patient with HIV: uncovering adrenal insufficiency from fluticasone-cobicistat interactions. [PDF]
CMAJDienes S, Nunn R, Lai A.
europepmc +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Chronic multifocal collagenous fibroma with tumor development at surgical incision site: a 46-year case report. [PDF]
Discov OncolLi X +7 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source