Results 121 to 130 of about 634,676 (271)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Delta neutrophil index, CRP/albumin ratio, procalcitonin, immature granulocytes, and HALP score in acute appendicitis: Best performing biomarker?

Open Medicine
This study investigates the diagnostic accuracy of five inflammatory biomarkers – delta neutrophil index (DNI); C-reactive protein/albumin ratio (CAR); procalcitonin (PCT); immature granulocytes count (IGc); and hemoglobin, albumin, lymphocyte, platelet ...
Cumaoglu Mustafa Oguz, Ayan Durmus, Vural Abdussamed, Dolanbay Turgut, Ozbey Caner, Kulu Abdul Ridvan   +5 more
doaj   +1 more source

Retrospective evaluation of novel serum inflammatory biomarkers in first-episode psychiatric disorders: diagnostic potential and immune dysregulation

Frontiers in Psychiatry
BackgroundThis study assessed the diagnostic capabilities of eight inflammatory biomarkers in first-episode schizophrenia (SCZ), bipolar disorder (BD), and depression (D), examining their differential expression across these psychiatric disorders.
Min Qiu, Chenkai Zhang, Haiqing Zhang, Hao Chen, Yingjia Lei, Ping Li, Shaochuan Zhang   +6 more
doaj   +1 more source

The Causal Effect of Education on Health [PDF]

We study the contribution of health-related behaviors to the health-education gradient by distinguishing between short-run and long-run mediating effects:while in the former only current or lagged behaviors are taken into account, in the latter we ...
Brunello, Giorgio, Fort, Margherita, Schneeweis, Nicole, Winter-Ebmer, Rudolf   +3 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Protein networks are influenced by maternal BMI and differentiate preterm birth types

Communications Medicine
Background Preterm birth remains a leading cause of neonatal morbidity and mortality. It is classified as spontaneous, characterized by the unexpected onset of labor, or medically indicated, resulting from obstetric intervention due to pregnancy ...
Paola A. Lopez Zapana, Chelsea A. DeBolt, Luka Karginov, Valerie Riis, Liqhwa Ncube, Andrea G. Edlow, Michal A. Elovitz, Douglas A. Lauffenburger   +7 more
doaj   +1 more source

An Enhanced Gravity Model for Determining Crucial Nodes in Social Networks Based on Degree K-Shell Eigenvector Index

IEEE Access
In the realm of network science, determining crucial nodes within a social network is an ongoing concern. As a result, it garners a lot of attention, and various centrality measures for the identification of crucial nodes have been proposed thus far ...
Hardeep Singh, Hardeep Singh
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Value of elastography in characterization of solid renal masses

African Journal of Urology
Background Solid renal masses often come to light as incidental findings during abdominal ultrasound examinations. Once detected, determining whether a renal mass is benign or malignant becomes imperative for informed decision-making regarding management
Ahmed Hazem Abbassy, Ayah Adel Emara, Nadine Rashad Barsoum, Galal Mohamed El Shorbagy   +3 more
doaj   +1 more source