Results 61 to 70 of about 627,001 (273)

Bayesian model selection for dark energy using weak lensing forecasts

, 2013
The next generation of weak lensing probes can place strong constraints on cosmological parameters by measuring the mass distribution and geometry of the low redshift universe.
Debono, Ivan
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

ANALISIS VALIDITAS RELIABILITAS TINGKAT KESUKARAN DAN DAYA BEDA PADA BUTIR SOAL UJIAN AKHIR SEMESTER GANJIL MATA PELAJARAN MATEMATIKA KELAS XII IPS DI SMA NEGERI 12 BANDAR LAMPUNG TAHUN AJARAN 2014/2015

Al-Jabar, 2015
This study aims to(1) determinethe items quality of odd semesterfinal examin social class XII mathematics subject academic year 2014/2015 in terms of validity, reliability, level of difficulty, and distinguishing power, (2) createa program shape for ...
Hery Susanto, Achi Rinaldi, Novalia Novalia   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Investments in stock of banks implementing high social responsibility standards listed on the Warsaw Stock Exchange

Copernican Journal of Finance & Accounting, 2014
The paper characterizes benefits and evaluates profitability of investments in stock of banks participating in RESPECT Index, i.e. a special index distinguishing companies that implement high standards of corporate social responsibility.
Michał Buszko
doaj   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

General neighbour-distinguishing index via chromatic number

Discrete Mathematics, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Horňák, Mirko, Soták, Roman
openaire   +3 more sources

Systemic inflammation response index is a useful indicator in distinguishing MOGAD from AQP4-IgG-positive NMOSD

Frontiers in Immunology
ObjectiveTo identify reliable immune-inflammation indicators for distinguishing myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) from anti–aquaporin-4 immunoglobulin G (AQP4-IgG)-positive neuromyelitis optica spectrum disorders ...
Lei Wang, Ruihong Xia, Xiangliang Li, Jingli Shan, Shengjun Wang   +4 more
doaj   +1 more source