Results 81 to 90 of about 627,001 (273)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Edge motion and the distinguishing index
Theoretical Computer Science, 2017 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Distinguishing number and distinguishing index of lexicographic product of two graphs
, 2016 11 pages, 2 figures.
Alikhani, Saeid, Soltani, Samaneh
openaire +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
The value of Mentzer index in the diagnosis of children thalassemia minor
HematologyObjective: To explore the effect of the Mentzer Index (MI) in screening for children thalassemia (TT) minor.Methods: We determined the MI cutoff value of diagnosing TT minor in children by utilizing a receiver operating characteristic (ROC) curve ...
Tao Wu +4 more
doaj +1 more source
Distinguishing number and distinguishing index of Kronecker product of two graphs
, 2016 The distinguishing number (index) $D(G)$ ($D'(G)$) of a graph $G$ is the least integer $d$ such that $G$ has an vertex labeling (edge labeling) with $d$ labels that is preserved only by a trivial automorphism. The Kronecker product $G\times H$ of two graphs $G$ and $H$ is the graph with vertex set $V (G)\times V (H)$ and edge set $\{\{(u, x), (v, y)\} |
Alikhani, Saeid, Soltani, Samaneh
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Scientific ReportsDiabetes retinopathy prevention necessitates early detection, monitoring, and treatment. Non-invasive optical coherence tomography (OCT) shows structural changes in the retinal layer. OCT image evaluation necessitates retinal layer segmentation.
Hamid Riazi-Esfahani +9 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source