Results 41 to 50 of about 149,234 (263)

MRI distortion correction is associated with improved local control in stereotactic radiotherapy for brain metastases

Scientific Reports
Distortions in brain MRI caused by gradient nonlinearities may reach several millimeters, thus distortion correction is strongly recommended for radiotherapy treatment planning.
Daniel Höfler, Johanna Grigo, Hadi Siavosch, Marc Saake, Manuel Alexander Schmidt, Thomas Weissmann, Philipp Schubert, Raphaela Voigt, Sebastian Lettmaier, Sabine Semrau, Arnd Dörfler, Michael Uder, Christoph Bert, Rainer Fietkau, Florian Putz   +14 more
doaj   +1 more source

Ultrafast dynamics of heme distortion in the O2-sensor of a thermophilic anaerobe bacterium

Communications Chemistry, 2021
Dioxygen protein sensors undergo structural distortions upon binding, but the role of heme distortion in allostery is unclear. Here heme distortion in a bacterial dioxygen sensor is studied using picosecond time-resolved electronic absorption ...
Olga N. Petrova, Byung-Kuk Yoo, Isabelle Lamarre, Julien Selles, Pierre Nioche, Michel Negrerie   +5 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Fixed operating frequency off-time control strategy for Boost PFC converters

Dianzi Jishu Yingyong, 2018
This paper proposes an improved turn-off time control strategy for the problem of the AC input current distortion that may occur after switching the operating mode of the Boost PFC converter. This strategy does not require multiple operating modes.
Jia Shi, Yan Limin, Sun Die
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Environmental Controls, Scarcity Rents, and Pre-existing Distortions [PDF]

Journal of Public Economics, 2001
Abstract One might suppose that an emissions tax has an advantage over command and control (CAC) regulations since it raises revenue that can be used to cut other distorting taxes. In this paper, we show that the focus on revenue raising is misplaced.
Don Fullerton, Gilbert E. Metcalf
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Playout buffer control for cbr traffic

Communications, 2000
Networks based on the packet switching principle introduce a new type of the continuous signal distortion which is caused by a random delay of packets. To eliminate this distortion, playout buffers are introduced.
Martin Klimo
doaj   +1 more source