Results 121 to 130 of about 1,044,921 (305)

Distress screening using distress thermometer

open access: yesIndian Journal of Palliative Care, 2014
Yasri, Sora, Wiwanitkit, Viroj
openaire   +2 more sources

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

open access: yesAdvanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen   +19 more
wiley   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

open access: yesAdvanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong   +14 more
wiley   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

open access: yesAdvanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi   +12 more
wiley   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang   +12 more
wiley   +1 more source

Exploring Men's Coping With Psychological Distress Within the Context of Conforming to Masculine Role Norms [PDF]

open access: yes, 2013
The purpose of this study was to explore the relationships among masculine and coping variables with psychological distress. It also identified the extent to which masculine variables and coping styles contributed to psychological distress, in a sample ...
Moodley, Komala G.
core  

An empirical analysis of the effect of financial distress on trade credit

open access: yes, 2003
This paper studies the use of supplier's trade credit by firms in financial distress. Trade credit represents a large portion of firms’ short-term financing and plays an important role in financial distress. We find that firms in financial distress use a
Preve, Lorenzo
core   +1 more source

Eustress and distress

open access: yesFolia Pharmacologica Japonica, 2007
「ストレス」という言葉は,日常生活で身近によく使われている.一般にストレスという言葉はネガティブな意味が強く,生活にとって好ましくないものという響きがある.確かに,われわれの身の回りにある多種のストレスにより,からだやこころの健康が脅かされ,その結果,身体の不調,疾患へとつながっていくことが少なくない.しかし,近年の分子生物学の進展に伴い,われわれの生体には極めて精巧な防御システムが構築されており,ホメオスタシスを維持するためのシステム,仕組みができていることも分かってきた.ストレス,すなわち外からのシグナルを受けて,生体は巧みに応答する.場合によってはストレスをうまく利用して,生体を常によい状態に保つようにしている.多くのストレスが,時によってはよいシグナル,よいストレスとなることもある ...
openaire   +3 more sources

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

Moral distress in emergency nurse: from analysis of cause to strategy of intervention

open access: yes, 2022
reservedABSTRACT BACKGROUND Il moral distress nei professionisti della salute rappresenta un problema rilevante a livello mondiale. Esso colpisce una significativa percentuale di infermieri, e in particolare gli infermieri di pronto soccorso, provocando
MASTELLARO, LIDIA
core  

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