Results 151 to 160 of about 1,841,492 (309)

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Policy responses to a dark side of the integration of regions [PDF]

In his paper I study policy responses to an increase in post-merger distress. I consider the integration of regions as a merger of populations which I view as a revision of social space, and I identify the effect of the merger on aggregate distress.
Stark, Oded
core  

Somewhat distressing [PDF]

British Dental Journal, 2009
openaire   +2 more sources

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Diabetes Distress Scale (DDS-17): European Portuguese Validation. [PDF]

Arch Endocrinol Metab
Melo MISPT, Falcão D, Campos DI, Santos MMD, Hernâni-Eusébio J, Silva AB.   +5 more
europepmc   +1 more source

A Leaf‐Inspired Janus‐Structured Triboelectric‐Moisture Hybrid Energy Harvester

Advanced Energy Materials, EarlyView.
This study proposes a bioinspired Janus structured energy‐leaf with hybrid triboelectric‐moisture hybrid energy harvesters. This hybrid energy harvester is demonstrated in an intelligent emergency system for effective distress signaling and evacuation guiding during potential crises.
Liang Wei, Rui Gu, Yixuan Fu, Ziwei Huo, Chao Liu, Jiahong Yang, Siqi Sun, Yang Liu, Qijun Sun, Dong‐Hwan Kim, Zhong Lin Wang   +10 more
wiley   +1 more source

A longitudinal network analysis of pain, psychological processes and psychological and sexual distress in women with endometriosis. [PDF]

Br J Health Psychol
Carvalho SA, Patafio B, Pascoal PM, Lapa T, Skvarc D.   +4 more
europepmc   +1 more source

Gender Disparities in the Prevalence, Trends, and Determinants of Later‐Life Urinary Incontinence: A Disproportionate Burden on Women

AGING MEDICINE, EarlyView.
This study shows that UI prevalence rose steadily in both the USA and UK during the 2010s, driven by aging, comorbidities, and educational changes, with women accounting for 65% of the projected increase in UI cases by 2030. These findings underscore the need for gender‐responsive UI prevention and care strategies, including targeted interventions for ...
Xiyin Chen, Shaoxiang Jiang, Muqi Guo, Hao Zhang, Mouwang Zhou, Yao Yao   +5 more
wiley   +1 more source

Trajectories of psychological distress and spinal pain in manual therapists during the COVID-19 pandemic in Sweden. [PDF]

Sci Rep
Weiss N, Axén I, Hoekstra T, Skillgate E.   +3 more
europepmc   +1 more source