Results 101 to 110 of about 74,438 (274)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

System Identification and Fractional-Order Proportional–Integral–Derivative Control of a Distributed Piping System

Fractal and Fractional
The vibration of piping systems is one of the most important causes of accelerated equipment wear and reduced work efficiency and safety. In this study, an active vibration control method based on a fractional-order proportional–integral–derivative (PID)
Xiaomeng Zhang, Shuo Zhang, Furui Xiong, Lu Liu, Lichuan Zhang, Xuan Han, Heng Wang, Yanzhu Zhang, Ranzhen Ren   +8 more
doaj   +1 more source

A numerical method for solving distributed-order multi-term time-fractional telegraph equations involving Caputo and Riesz fractional derivatives

An International Journal of Optimization and Control: Theories & Applications (IJOCTA)
This paper introduces a robust distributed-order time-fractional telegraph model, incorporating Caputo time- and Riesz space-fractional derivatives. The spatial Riesz derivative is discretized using an optimized finite difference method. For the distributed-order fractional operator, the midpoint rule was first used to approximate the integral with ...
Safar Irandoust Pakchin, Mohammad Hossein Derakhshan, Shahram Rezapour   +2 more
openaire   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

An Analysis of Controllability Criteria for Higher-Order Caputo Fractional Differential Systems With State and Control Delays

International Journal of Differential Equations
The present study investigates the controllability problems for higher-order semilinear fractional differential systems (HOSLFDSs) with state and control delays in the context of the Caputo fractional derivative.
Anjapuli Panneer Selvam, Venkatesan Govindaraj, Raaid Alubady, Sina Etemad   +3 more
doaj   +1 more source

An accurate collocation method for distributed order time fractional nonlinear diffusion wave equation with error analysis

Results in Applied Mathematics
The distributed-order fractional nonlinear diffusion-wave problem is a mathematical model that combines the concepts of fractional calculus and nonlinear diffusion-wave equations.
M. Taghipour, H. Aminikhah
doaj   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Putting an End to the Physical Initial Conditions of the Caputo Derivative: The Infinite State Solution

Fractal and Fractional
In this paper, a counter-example based on a realistic initial condition invalidates the usual approach related to the so-called physical initial condition of the Caputo derivative used to solve fractional-order Cauchy problems.
Jean-Claude Trigeassou, Nezha Maamri
doaj   +1 more source