Results 71 to 80 of about 4,198,966 (245)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Distributed dynamic mapping scheme based on cost function

open access: yesTongxin xuebao, 2014
For supporting efficient host mobility and mapping identifiers onto locators,a distributed dynamic mobility mapping scheme based on cost function was proposed.In the scheme,depending on the mobility pattern and communication feature,the communication of ...
Guo-dong GE   +3 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Five points on columns

open access: yesFrontiers in Neuroanatomy, 2010
“Column,” like “gene,” has both conceptual and linguistic shortcomings. The simple question “what is a column” is not easy to answer and the word itself is not easy to replace.
Kathleen S Rockland
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Research Directions in Distributed Systems. [PDF]

open access: yes, 1999
This paper considers the technical characteristics of current distributed systems technology as exemplified by CORBA. In the context of large-scale globally distributed applications, potential problems are highlighted, and areas for further research and ...
Marshall, I. W.   +2 more
core   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Reflection on Network Element Evolution of Big Data Management for Telecom Operators

open access: yesDianxin kexue, 2015
Big data has had a profound impact on the future of telecommunications operators,and perhaps even subversive type business model change.The present situation of the application of big data and existing problems of telecom operators were analyzed,and the ...
Jun Zhao, Yirong Shi
doaj  

The impact of variability and distribution of practice on student’s learning of basketball throw skill

open access: yesPedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2019
Purpose: The practice organization is an important factor in sports environment and education. This study aimed to investigate the impact of variability and distribution of practice on basketball throw skill learning among female elementary school ...
Gh. Lotfi, M. Baghaeyan, N. Baghaee
doaj   +1 more source

Design Support for Distributed Systems: DSE4DS [PDF]

open access: yes, 2002
Distributed System design is a highly complicated and non-trivial task. The problem is characterized by the need to design multi-threaded, multi-processor, and multi-media systems.
Derrick, John   +3 more
core  

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