Results 61 to 70 of about 8,190 (220)
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Active Inference in Distributed Computing Continuum Systems [PDF]
Modern distributed systems also deal with uncertain scenarios, where environments, infrastructures, and applications are widely diverse. In the scope of IoT-Edge-Fog-Cloud computing, leveraging these neuroscience-inspired principles and mechanisms could ...
Dustdar, Schahram; orcid:
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Operating distributed computing continuum systems through active inference [PDF]
Distributed computing continuum systems combine various computational layers into one cohesive platform. Thus, clients can benefit both from low-latency computations, i.e., from Edge devices, as well as highly available and virtually unlimited resources,
Sedlak, Boris; orcid:
core
Molecular dynamics for fluid mechanics in arbitrary geometries [PDF]
, 2008 Simulations of nanoscale systems where fluid mechanics plays an important role are required to help design and understand nano-devices and biological systems.
Reese, Jason M. +5 more
core +1 more source
Active Inference for Distributed Intelligence in the Computing Continuum [PDF]
Modern distributed systems deal with uncertain scenarios, where environments, infrastructures, and applications are widely diverse. In the scope of IoT-Edge-Fog-Cloud computing, leveraging these neuroscience-inspired principles and mechanisms could aid ...
Dustdar, Schahram; orcid:
core +4 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Engineering the New Fabric of the Distributed Systems Computing Continuum [PDF]
, 2022 As humans, things, software and AI continue to become the entangled fabric of distributed systems, systems engineers and researchers are facing novel challenges. In this talk, we analyze the role of IoT, Edge, and Cloud, as well as AI in the co-evolution
Dustdar, Schahram; orcid:
core
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Optimization and Orchestration in the Cloud-to-Edge Computing Continuum [PDF]
In this thesis, we improve existing orchestration techniques to address the new challenges the Cloud-to-Edge Computing Continuum raises. Edge computing is a paradigm that moves computation and storage outside of the data centers to the edge of the ...
RAC, Samuel
core