Results 61 to 70 of about 862,924 (286)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra   +3 more
wiley   +1 more source

Creating a Relational Distributed Object Store [PDF]

open access: yes, 2013
In and of itself, data storage has apparent business utility. But when we can convert data to information, the utility of stored data increases dramatically. It is the layering of relation atop the data mass that is the engine for such conversion.
Lin, Wayzen   +2 more
core  

Datacloud - Distributed architecture for data storing and sharing

open access: yes, 2019
{"references": ["https://datacloud.helsinki.fi", "https://en.wikipedia.org/wiki/Ceph_(software)", "https://en.wikipedia.org/wiki/Amazon_S3", "https://en.wikipedia.org/wiki/Software-defined_storage", "https://whatis.techtarget.com/definition/commodity-ha rdware", "https://en.wikipedia.org/wiki/HAProxy", "https://bit.ly/2UYPieK"]}
Tenhunen, Ville   +2 more
openaire   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

SIMHAR - Smart Distributed Web Crawler for the Hidden Web Using SIM+Hash and Redis Server

open access: yesIEEE Access, 2020
Developing a distributed web crawler obliges major engineering challenges, all of which are eventually associated to scale. To retain corpus of search engine and a reasonable state of freshness, the crawler must be distributed over multiple computers. In
Sawroop Kaur, G. Geetha
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Online Replication Strategies for Distributed Data Stores

open access: yes, 2019
EC/H2020/679158/EU/Resolving the Tussle in the Internet: Mapping, Architecture, and Policy Making ...
Semmler, Niklas   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A numerical method for efficient 3D inversions using Richards equation

open access: yes, 2017
Fluid flow in the vadose zone is governed by Richards equation; it is parameterized by hydraulic conductivity, which is a nonlinear function of pressure head.
Cockett, Rowan   +2 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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