Results 71 to 80 of about 862,924 (286)
Storage and Search in Dynamic Peer-to-Peer Networks
, 2013 We study robust and efficient distributed algorithms for searching, storing, and maintaining data in dynamic Peer-to-Peer (P2P) networks. P2P networks are highly dynamic networks that experience heavy node churn (i.e., nodes join and leave the network ...
Augustine John +6 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
CATS: linearizability and partition tolerance in scalable and self-organizing key-value stores [PDF]
, 2012 Distributed key-value stores provide scalable, fault-tolerant, and self-organizing storage services, but fall short of guaranteeing linearizable consistency in partially synchronous, lossy, partitionable, and dynamic networks, when data is distributed
Arad, Cosmin +2 more
core
A Practical Distributed Universal Construction with Unknown Participants
, 2014 Modern distributed systems employ atomic read-modify-write primitives to coordinate concurrent operations. Such primitives are typically built on top of a central server, or rely on an agreement protocol. Both approaches provide a universal construction,
Felber, Pascal +2 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
An Agglomerative-adapted Partition Approach for Large-scale Graphs
International Journal of Librarianship, 2019 In recent years, an increasing number of knowledge bases have been built using linked data, thus datasets have grown substantially. It is neither reasonable to store a large amount of triple data in a single graph, nor appropriate to store RDF in named ...
Chen Tao +4 more
doaj +1 more source
A scale-out RDF molecule store for distributed processing of biomedical data [PDF]
, 2008 The computational analysis of protein-protein interaction and biomolecular pathway data paves the way to efficient in silico drug discovery and therapeutic target identification.
Bouton, Chris +4 more
core
On the Energy Proportionality of Distributed NoSQL Data Stores [PDF]
, 2015 The computing community is facing several big data challenges due to the unprecedented growth in the volume and variety of data. Many large-scale Internet companies use distributed NoSQL data stores to mitigate these challenges. These NoSQL data-store installations require massive computing infrastructure, which consume significant amount of energy and
Balaji Subramaniam, Wu-chun Feng
openaire +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Authenticating Health Activity Data Using Distributed Ledger Technologies
Computational and Structural Biotechnology Journal, 2018 The on-demand digital healthcare ecosystem is on the near horizon. It has the potential to extract a wealth of information from “big data” collected at the population level, to enhance preventive and precision medicine at the patient level.
James Brogan +2 more
doaj +1 more source