Results 81 to 90 of about 444,586 (306)
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Network Optimization for Distributed Memory File System on High Performance Computers [PDF]
, 2017 Chunjia Wu, Guangming Liu, Xin Liu
openalex +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Research on the selection of grid data storage technology
Dianxin kexue, 2018 Unstructured data and real-time data were storaged by state grid company’s big data platform distributed file system (based on HDFS optimized package).Based on HDFS optimized packaging,HDFS was characterized by high fault tolerance,low cost and high ...
Chengling LI +4 more
doaj +2 more sources
Research and Application of Datengxia Project Archives Management System
Renmin Zhujiang, 2022 In order to realize the comprehensive automation of the file management business process of the Datengxia Water Control Project and improve the informatization level of carrier file management and utilization, the metadata solution of xml technology and ...
WANG Jue, QIU Shineng
doaj
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Security in Distributed File System
International Journal of Innovative Technology and Exploring Engineering, 2019 The investigation of little documents is required to give singular clients the most recent data and improved administrations. Every one of the machines is required to be under a typical director and have the option to impart safely. Huge information is the center subject in enterprises and research fields just as for society overall. Hadoop is the most
openaire +1 more source