Results 61 to 70 of about 6,540 (265)

Distributed Control for Time-Fractional Differential System Involving Schrödinger Operator

Journal of Function Spaces, 2019
In this paper, we investigate the distributed optimal control problem for time-fractional differential system involving Schrödinger operator defined on Rn. The time-fractional derivative is considered in the Riemann-Liouville sense.
Abd-Allah Hyder, M. EL-Badawy
doaj   +1 more source

Generating novel probability distributions: A UD fractional derivative approach

Journal of Statistical Research
This study introduces novel probability distributions derived from the Dixit and Ujlayan (UD) fractional differential equation. By applying the UD fractional differential equation to established continuous probability distributions, new probability distributions are formulated.
Alaa Jamal, Iyad Alhribat, Monjed H Samuh   +2 more
openaire   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Finite Difference and Chebyshev Collocation for Time-Fractional and Riesz Space Distributed-Order Advection–Diffusion Equation with Time-Delay

Fractal and Fractional
In this paper, we have established a numerical method for a class of time-fractional and Riesz space distributed-order advection–diffusion equation with time-delay.
Fang Wang, Yuxue Chen, Yuting Liu
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Optimal feedback stabilization of fractional output in semilinear distributed systems

Partial Differential Equations in Applied Mathematics
This study explores the stabilization of state–space fractional derivatives in semilinear distributed systems, using the Riemann–Liouville derivative of order α, where α lies within the interval 0,1.
Marouane Karim, Issam Khaloufi, Imane Dehaj, Rachik Mostafa   +3 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

MAS-Based Decentralized Coordinated Control Strategy in a Micro-Grid with Multiple Microsources

Energies, 2020
In this paper, a decentralized coordinated control method based on multi-agent system is proposed to improve the voltage stability of micro-grid. In lower-level agents, the decentralized control is designed as double-loop controllers for the inverter of ...
Shiyun Xu, Huadong Sun, Zhanqiang Zhang, Qiang Guo, Bin Zhao, Jingtian Bi, Bo Zhang   +6 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source