Results 161 to 170 of about 662,368 (316)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A Load Transfer Scheme of Radial Distribution Feeders Considering Distributed Generation
, 2012 [[abstract]]This work proposes a load transfer scheme for radial distribution feeders with distributed generation units. A distribution feeder may be operated with distributed generation units in parallel.
Yang, Wen-Chih; Huang, Wei-Tzer
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Distributed multi-generation systems: energy models and analyses [PDF]
, 2009 Libro riguardante la caratterizzazione di sistemi per la produzione combinata di energia da sistemi di multi-generazione distribuita (Distributed Multi-Generation, DMG).
Chicco, Gianfranco +1 more
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Supporting transient stability in future highly distributed power systems
, 2010 Incorporating a substantial volume of microgeneration (consumer-led rather than centrally planed) within a system that is not designed for such a paradigm could lead to conflicts in the operating strategies of the new and existing centralised generation ...
Burt, Graeme +2 more
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Correction: Parallel operated hybrid Arithmetic-Salp swarm optimizer for optimal allocation of multiple distributed generation units in distribution networks. [PDF]
PLoS One, 2023 Anjum ZM +4 more
europepmc +1 more source
Distributed Generation Investment by a Microgrid UnderUncertainty [PDF]
, 2006 This paper examines a California-based microgrid s decision to invest in a distributed generation (DG) unit that operates on natural gas. While the long-term natural gas generation cost is stochastic, we initially assume that the microgrid may purchase ...
Siddiqui, Afzal, Marnay, Chris
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source