Results 211 to 220 of about 2,427,950 (333)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Optimal regulation under unknown supply of distributed generation [PDF]

As distributed generation (DG) continues to expand, larger low-voltage networks will be required in the future. However, regulated distribution network operators (DNOs) need to invest in new infrastructure without knowing a relevant determinant of ...
Rob Aalbers, Victoria Shestalova, Viktoria Kocsis   +2 more
core  

Analysis of power system transient stability with PSO-optimized distributed generation and HVDC transmission systems. [PDF]

Sci Rep
Jang J, Gong Y, Min S, Kim I.
europepmc   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Optimal placement of distributed generation to minimize power loss and improve voltage stability. [PDF]

Heliyon
Adegoke SA, Sun Y, Adegoke AS, Ojeniyi D.   +3 more
europepmc   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Entrepreneurship, sustainability, and solar distributed generation

Entrepreneurship and Sustainability Issues, 2016
Wadim Strielkowski
doaj   +1 more source

Optimal distributed generation placement and sizing using modified grey wolf optimization and ETAP for power system performance enhancement and protection adaptation. [PDF]

Sci Rep
Bouchikhi N, Boussadia F, Bouddou R, Salau AO, Mekhilef S, Gouder C, Adiche S, Belabbes A.   +7 more
europepmc   +1 more source

A flexible and distributed architecture for adaptive end-to-end QoS provisioning in next-generation networks [PDF]

, 2005
Jie Yang, Jian Ye, Symeon Papavassiliou, Nirwan Ansari   +3 more
openalex   +1 more source

A Generalization of Generalized Gamma Distribution [PDF]

International Journal of Computational and Theoretical Statistics, 2019
Shukla Kamlesh Kumar, Shanker Rama
openaire   +2 more sources