Results 81 to 90 of about 13,322,968 (309)
Time-optimal control of infinite order distributed parabolic systems involving time lags
Beni-Suef University Journal of Basic and Applied Sciences, 2014 A time-optimal control problem for linear infinite order distributed parabolic systems involving constant time lags appear both in the state equation and in the boundary condition is presented.
G.M. Bahaa
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Oscillation Criteria for Even Order Neutral Equations with Distributed Deviating Argument
International Journal of Differential Equations, 2010 We present new oscillation criteria for the even order neutral delay differential equations with distributed deviating argument [r(t)ψ(x(t))Z(n−1)(t)]′+∫abp(t,ξ)f[x(g(t,ξ))]dσ(ξ)=0, t≥t0, where Z(t)=x(t)+q(t)x(t−τ).
Siyu Zhang, Fanwei Meng
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Distributed Scaffolding Influences in Inquiry Learning on High Order Thinking Skills
Jurnal Pendidikan Sains, 2018 : The study aims to investigate the effect of distributed scaffolding in inquiry learning to higher order thinking skills (HOTS) of students, especially on optical geometry subject.
Muji Sobirin +2 more
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Second-Order Weight Distributions [PDF]
IEEE Transactions on Information Theory, 2011 10 pages, accepted for publication in IEEE Transactions on Information Theory, May ...
openaire +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Distributed transformer for high order epistasis detection in large-scale datasets
Scientific ReportsUnderstanding the genetic basis of complex diseases is one of the most important challenges in current precision medicine. To this end, Genome-Wide Association Studies aim to correlate Single Nucleotide Polymorphisms (SNPs) to the presence or absence of ...
Miguel Graça +3 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
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