Results 91 to 100 of about 8,632,140 (300)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Power management for hybrid distributed generation systems

International Journal of Sustainable Engineering, 2018
The design of a new power management tool able to manage the power flow from different renewable energy sources is proposed in this paper. PV and wind are the primary power sources for the system, and a fuel cell with electrolyser and batteries are used ...
H. Yousef, A. H. Al-Badi, A. Polycarpou
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Required VSC efficiency for zero net-loss distribution network active compensation

Active compensation of distribution networks with medium-voltage power electronics can result in a reduction in feeder electrical losses if operated correctly, however losses are incurred in the active compensator itself when operating.

core   +1 more source

Multiple-criteria decision-making of distribution system planning considering distributed generation

, 2012
This paper investigates multi-criteria decision-making of power distribution system planning with different types of distributed generations. Uncertainties of the distributed generations make it difficult to determine the exact numerical values of the ...
Zhenzhi Lin, Fushuan Wen, Xue Xiao, Lin, Zhenzhi, Xiao, Xue, Jiansheng Huang, Wen, Fushuan, Huang, Jiansheng (R9337)   +7 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The role of power system flexibility in generation planning [PDF]

, 2011
Paper presented at the IEEE 2011, Power and Energy Society General Meeting, San Diego, CA, 24-29 July 2011As the penetration of variable renewable generation increases in power systems worldwide, planning for the effects of variability will become more ...
Eamonn Lannoye, Lannoye, Eamonn, O\u27Malley, Mark, O'Malley, Mark, Mark O'Malley, Flynn, Damian, Damian Flynn   +6 more
core   +1 more source

Determining the optimal bid direction of a generation company using the gradient vector of the profit function in the network constraints of the electricity market

IET Generation, Transmission & Distribution
One of the primary challenges faced by generation companies (GenCos), which operate multiple generation units within the electricity market, is the determination of the optimal bid price for these units to maximize profit.
Mohammad Ebrahim Hajiabadi, Mahdi Samadi, Mohammad Hassan Nikkhah, Hossein Lotfi, Li Li   +4 more
doaj   +1 more source