FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Checking sequences for distributed test architectures [PDF]
, 2008 Controllability and observability problems may manifest themselves during the application of a checking sequence in a test architecture where there are multiple remote testers.
Hierons, RM, Ural, H
core +3 more sources
Transient Behavior of a Queueing Model with Hyper-Exponentially Distributed Processing Times and Finite Buffer Capacity. [PDF]
Sensors (Basel), 2022 Kempa WM, Paprocka I.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male mice. [PDF]
Nat Commun, 2023 Choi K +8 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Streaming, distributed variational inference for Bayesian nonparametrics
, 2015 This paper presents a methodology for creating streaming, distributed inference algorithms for Bayesian nonparametric (BNP) models. In the proposed framework, processing nodes receive a sequence of data minibatches, compute a variational posterior for ...
Fisher, John W +3 more
core
Joint Implicit and Explicit Neural Networks for Question Recommendation in CQA Services
IEEE Access, 2018 Community question answering (CQA) services have emerged as a type of popular social platforms. In the social network, experts provide knowledgeable answers to the questions in their domain of expertise, while celebrities publish influential opinions ...
Hongkui Tu +3 more
doaj +1 more source
Communications of the ACM, 1978 A language concept for concurrent processes without common variables is introduced. These processes communicate and synchronize by means of procedure calls and guarded regions. This concept is proposed for real-time applications controlled by microcomputer networks with distributed storage.
openaire +3 more sources