Results 61 to 70 of about 247,233 (313)

Distance-Constraint k-Nearest Neighbor Searching in Mobile Sensor Networks

open access: yesSensors, 2015
The κ -Nearest Neighbors ( κNN) query is an important spatial query in mobile sensor networks. In this work we extend κNN to include a distance constraint, calling it a l-distant κ-nearest-neighbors ( l ...
Yongkoo Han   +4 more
doaj   +1 more source

ParSCL: A Parallel and Distributed Framework to Process All Nearest Neighbor Queries on a Road Network

open access: yesIEEE Access, 2023
The proliferation of current and next-generation mobile and sensing devices has increased at an alarming rate. With these state-of-the-art devices, the global positioning system (GPS) has made remote sensing and location tracking more viable.
Aavash Bhandari   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Efficient spatial data partitioning for distributed $$k$$ k NN joins

open access: yesJournal of Big Data, 2022
Parallel processing of large spatial datasets over distributed systems has become a core part of modern data analytic systems like Apache Hadoop and Apache Spark.
Ayman Zeidan, Huy T. Vo
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Efficient Processing of Continuous Skyline Query over Smarter Traffic Data Stream for Cloud Computing

open access: yesDiscrete Dynamics in Nature and Society, 2013
The analyzing and processing of multisource real-time transportation data stream lay a foundation for the smart transportation's sensibility, interconnection, integration, and real-time decision making.
Wang Hanning   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Scaling Heterogeneous Databases and the Design of Disco [PDF]

open access: yes, 1996
Access to large numbers of data sources introduces new problems for users of heterogeneous distributed databases. End users and application programmers must deal with unavailable data sources.
Anthony Tomasic
core   +1 more source

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