Results 51 to 60 of about 2,422 (292)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Persistent Scatterer Pair Interferometry: Approach and Application to COSMO-SkyMed SAR Data

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2014
Persistent scatterer interferometry is a widely used technique to detect and monitor slow terrain movements, with millimetric accuracy, from satellite synthetic aperture radar (SAR) data.
Mario Costantini   +5 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

A Review of Ten-Year Advances of Multi-Baseline SAR Interferometry Using TerraSAR-X Data

open access: yesRemote Sensing, 2018
Since its launch in 2007, TerraSAR-X has continuously provided spaceborne synthetic aperture radar (SAR) images of our planet with unprecedented spatial resolution, geodetic, and geometric accuracy.
Xiao Xiang Zhu   +3 more
doaj   +1 more source

Development of an Imagewise Stacking Method to Mitigate Atmospheric Effect With an Application to Lianyan Railway

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021
Much attention has been paid to the subsidence monitoring of large-scale man-made linear features, which are usually characterized by long-distance, large-scale, and nonuniform distribution.
Zhuang Gao   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Retrieval of {Phase} {History} {Parameters} from {Distributed} {Scatterers} in {Urban} {Areas} {Using} {Very} {High} {Resolution} {SAR} {Data}

open access: yes, 2012
In a recent contribution Ferretti and co-workers (Ferretti, A., Fumagalli, A., Novali, F., Prati, C., Rocca, F., Rucci, A., 2011. A new algorithm for processing interferometric data-stacks: SqueeSAR IEEE Transactions on Geoscience and Remote Sensing 49(9)
Wang, Yuanyuan;Zhu, Xiaoxiang;Bamler, Richard
core   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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