Results 61 to 70 of about 408,117 (264)

Research on selective trust-path search and aggregation in distributed environment

open access: yesTongxin xuebao, 2012
Current trust models based on reputation had some disadvantages in characterizing recommendation credibility and dealing with Trust-Path Search and aggregation.To solve these problems,an updating algorithm for recommendation credibility was proposed ...
Yan-lin QIN, Xiao-ping WU, Jian-xin GAO
doaj   +2 more sources

Fuzzy Distributed Hybrid Flow Shop Scheduling Problem With Heterogeneous Factory and Unrelated Parallel Machine: A Shuffled Frog Leaping Algorithm With Collaboration of Multiple Search Strategies

open access: yesIEEE Access, 2020
The single factory production is shifting to multi-factory production which brings new challenges. Hybrid flow shop problem (HFSP) as a common problem in production-manufacturing has been studied extensively, however distributed hybrid flow shop problem (
Lei Wang, Dongdong Li
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Distributed Searching of Partial Grids

open access: yesCoRR, 2016
We consider the following distributed pursuit-evasion problem. A team of mobile agents called searchers starts at an arbitrary node of an unknown $n$-node network. Their goal is to execute a search strategy that guarantees capturing a fast and invisible intruder regardless of its movements using as few agents as possible.
Dariusz Dereniowski, Dorota Urbanska
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Calibration of SAR Polarimetric Images by Covariance Matching Estimation Technique with Initial Search

open access: yesRemote Sensing
To date, various methods have been proposed for calibrating polarimetric synthetic aperture radar (SAR) using distributed targets. Some studies have utilized the covariance matching estimation technique (Comet) for SAR data calibration.
Jingke Liu, Lin Liu, Xiaojie Zhou
doaj   +1 more source

Promised and Distributed Quantum Search [PDF]

open access: yes, 2005
This paper gives a quantum algorithm to search in an set S for a k-tuple satisfying some predefined relation, with the promise that some components of a desired k-tuple are in some subsets of S. In particular when k=2, we show a tight bound of the quantum query complexity for the Claw Finding problem, improving previous upper and lower bounds by ...
openaire   +1 more source

Distributed indexing for semantic search [PDF]

open access: yesProceedings of the 3rd International Semantic Search Workshop, 2010
In this paper we describe the process of building indices for semantic search using MapReduce. We compare the two most straightforward representations of RDF data, the horizontal index structure using parallel indices and the vertical index structure using fields. We measure the cost of building indices and also compare retrieval performance on keyword
openaire   +1 more source

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