Results 121 to 130 of about 3,429,435 (288)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Security of the MaidSafe Vault Network [PDF]

open access: yes, 2014
The MaidSafe network is an open-source, decentralised, autonomous network for data storage and retrieval by end user applications. All data is stored on the network within vaults, which are member nodes of a self-managed network resembling a distributed ...
Paul, Greig   +2 more
core   +3 more sources

Phase transformation mechanism in lithium manganese nickel oxide revealed by single-crystal hard X-ray microscopy

open access: yesNature Communications, 2017
As an intercalation electrode material for lithium ion batteries, spinel LixMn1.5Ni0.5O4possesses a metastable nature during the electrochemical operation.
Saravanan Kuppan   +3 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Sigmoid(x): secure distributed network storage [PDF]

open access: yes, 2011
Secure data storage is a serious problem for computer users today, particularly in enterprise environments. As data requirements grow, traditional approaches of secured silos are showing their limitations. They represent a single – or at least, limited –
Irvine, James   +2 more
core   +3 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Power oscillation suppression strategy of VSG based on finite‐time Hamiltonian method

open access: yesIET Power Electronics
In order to improve the stability of the virtual synchronous generator (VSG) system and suppress the power oscillation, a power oscillation suppression strategy of VSG based on the finite‐time Hamiltonian method is proposed in this paper.
Guo Xiaomei, Yonggang Li, Yichen Zhou
doaj   +1 more source

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