Results 111 to 120 of about 345,966 (323)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Numerical simulations for matter transport by the interaction between bubbles and pressure waves near tissue boundaries

Journal of Fluid Science and Technology
The interaction between bubbles and tissues (bone and fat) in ultrasound and the mechanism of drug transport accompanied by bubble collapse were investigated numerically by using the ghost fluid methods with zonal grids.
Hisayoshi MURASAWA, Ryotaro KAMEDA, Hiroyuki TAKAHIRA   +2 more
doaj   +1 more source

Design of multi-layered porous fibrous metals for optimal sound absorption in the low frequency range

Theoretical and Applied Mechanics Letters, 2016
We present a design method for calculating and optimizing sound absorption coefficient of multi-layered porous fibrous metals (PFM) in the low frequency range.
Wenjiong Chen, Shutian Liu, Liyong Tong, Sheng Li   +3 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Polyimide-Based Flexible Microelectrode Array for Non-Invasive Transcorneal Electrical Stimulation

Sensors
Transcorneal electrical stimulation (TES) is a promising treatment for several retinal degenerative diseases (RDDs). TES involves the application of a controlled electrical current to the anterior surface of the cornea, aimed at activating the retina and
Víctor Manuel Carpio-Verdín, Natiely Hernández-Sebastián, Bernardino Barrientos-García, Silvia Solis-Ortiz, Erik R. Bojorges-Valdez, Francisco López-Huerta, Carlos Ismael Mares-Castro, Wilfrido Calleja-Arriaga   +7 more
doaj   +1 more source

Surface Modification of Glassy Carbon Electrode by Ni-Cu Nanoparticles as a Competitive Electrode for Ethanol Electro-Oxidation [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2018
In the present study, Nickel-Copper nanoparticles were electrodeposited on glassy carbon electrode (GCE) by using electroplating deposition method. The prepared electrode was characterized by scanning electron microscopy (SEM) and elemental mapping ...
Abolfath Eshghi, Mehdi Kheirmand
doaj  

Smart materials application on high performance sailing yachts for energy harvesting [PDF]

, 2013
Piezoelectric patches are bounded on a keel bulb in order to harvest vibration energy by converting electrical output. Unsteady computational fluid dynamics method is also used to find the structural boundary condition such as the hydrodynamic pressure ...
Khorasanchi, Mahdi, Mylonas, Dimitrios, Turkmen, Serkan   +2 more
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The Corrosion Behavior of C-steel, Al-alloy and Pure-Cu in Red Oak Wood Extract: A Comparative Study

International Journal of Electrochemical Science, 2019
The corrosion behavior of three metals (C-steel, Al-alloy, and Pure-Cu) in the red oak wood extract (ROWE) had been studied using weight loss (expressed as thickness loss), potentiodynamic polarization and electrochemical impedance spectroscopy.
Ehteram A. Noor, Azza A. Al-Ghamdi, Mohamed Abdel Salam   +2 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source