Results 101 to 110 of about 1,854,118 (269)

Design Support for Distributed Systems: DSE4DS [PDF]

, 2002
Distributed System design is a highly complicated and non-trivial task. The problem is characterized by the need to design multi-threaded, multi-processor, and multi-media systems.
Derrick, John, Waters, A. Gill, Akehurst, David H., Bordbar, Behzad   +3 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Using status messages in the distributed test architecture

, 2008
If the system under test has multiple interfaces/ports and these are physically distributed then in testing we place a tester at each port. If these testers cannot directly communicate with one another and there is no global clock then we are testing ...
Hierons, RM
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Distributed control of multi-robot systems using bifurcating potential fields

, 2010
The distributed control of multi-robot systems has been shown to have advantages over conventional single robot systems. These include scalability, flexibility and robustness to failures.
Derek J. Bennet, Colin R. McInnes, Bennet, Derek J., McInnes, C.R., McInnes, Colin R.   +4 more
core   +1 more source

Multi-GPU, Multi-Node Algorithms for Acceleration of Image Reconstruction in 3D Electrical Capacitance Tomography in Heterogeneous Distributed System. [PDF]

Sensors (Basel), 2020
Majchrowicz M, Kapusta P, Jackowska-Strumiłło L, Banasiak R, Sankowski D.   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A flexible and secure deployment framework for distributed applications

, 2004
This paper describes an implemented system which is designed to support the deployment of applications offering distributed services, comprising a number of distributed components.
McCarthy, Andrew, Dearle, Alan, Juan Carlos Diaz y Carballo, Andrew McCarthy, Kirby, Graham, Diaz y Carballo, Juan-Carlos, Alan Dearle, Graham Kirby   +7 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Rigorous Design of Distributed Transactions

Database replication is traditionally envisaged as a way of increasing fault-tolerance and availability. It is advantageous to replicate the data when transaction workload is predominantly read-only.
Yadav, Divakar
core