Results 101 to 110 of about 7,107,193 (299)

Cross‐sectional investigation of the distribution characteristics and prognostic significance of lateral lymph nodes in patients with rectal cancer

open access: yesCancer Medicine
Background Information about the distribution characteristics and prognostic significance of lateral lymph nodes (LLNs) on primary computed tomography (CT) scan in rectal cancer patients is lacking.
Xuyang Yang   +7 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Analysis on the characteristics of lightning current amplitude in Beijing area using ADTD data

open access: yes暴雨灾害, 2019
In order to investigate the characteristics of lightning current amplitude in Beijing area, the distribution law of current intensity and the cumulative probability distribution of current amplitude are analyzed based on ADTD data of 2009-2016.
Jinge GAO, Huiying WANG, Wen PIAO
doaj   +1 more source

Accounting for Poverty Differences between the United States, Great Britain, and Germany [PDF]

open access: yes
We propose a framework for comparing the relationship between poverty and personal characteristics across countries (or across years), and use it to compare levels and patterns of relative poverty in the USA, Great Britain and Germany during the 1990s ...
Martin Biewen, Stephen P. Jenkins
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Characteristics of ancient trees in different urbanization rates areas of Yi nationality in Yunnan Province

open access: yesGuangxi Zhiwu
The urbanization undoubtedly has a significant impact on minority cultures and the natural environment from which minority cultures are born, and they are closely intertwined in the birth and preservation of cultural diversity.
ZHENG Mengfei   +3 more
doaj   +1 more source

An Adaptive JPEG Double Compression Steganographic Scheme Based on Irregular DCT Coefficients Distribution

open access: yesIEEE Access, 2019
Steganography is to embed secret information into digital media and minimize the distortion caused by data embedding. The JPEG is a widely used image compression format, and many JPEG images transmitted on the network are double compressed.
Ju Jia, Zhaoxia Xiang, Lina Wang, Yan Xu
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Analysis of the Distribution Characteristics of Mountain Fires Based on the Disaster Data of Hubei Transmission Lines

open access: yes南方能源建设
[Introduction] The distribution characteristics of mountain fires by using the historical disaster data of mountain fires related to transmission lines in Hubei province has been analyzed. [Method] Based on the mountain fire disaster data of transmission
Limei YE   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy