Results 31 to 40 of about 1,026,061 (247)

Benchmarking the distribution coefficient of anticancer lead compounds using the predicted log D values of clinically approved chemotherapeutic drugs

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022
BACKGROUND: The distribution coefficient (Log D) can predict the solubility of a compound at a particular pH. In identifying lead compounds, Log D is helpful to predict the behavior, permeability, and clearance of a compound in the different organs.
Paolo Raphael Eclarin, Patricia Andrea Yan, Carlo Lorenzo Paliza, Blanche Ibasan, Patricia Rosemarie Basiloy, Nick Adrian Gante, Angelie Nicole Reyes, John Sylvester Nas   +7 more
doaj   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Influence of Organic Carbon from Weathered Sediments on Triclocarban Distribution in Environmental Aqueous Systems

Separations
In this study, the chemical distribution of triclocarban (TCC), in natural aqueous systems, between water and sediment, with different chemical compositions of the aqueous phase and different percentages of organic carbon (OC%) in the sediments is ...
Ion Ion, Raluca Madalina Senin, Alina Catrinel Ion   +2 more
doaj   +1 more source

PHENOLIC COMPOUNDS AND PECTIC SUBSTANCES OF EUROPEAN GOOSEBERRY LEAVES ΈGROSSULARIA RECLINATA ΈL.Ή MILL.Ή

Фармация и фармакология (Пятигорск), 2018
In the leaves of European gooseberry 23 compounds have been found, and only 13 of them have been identified by the presence of standards. One of the indicators of the bioavailability of drugs is the distribution coefficient of the substances under ...
S. L. Adjiahmetova, D. I. Pozdnyakov, N. M. Chervonnaya, L. P. Myikots, A. V. Voronkov, E. T. Oganesyan   +5 more
doaj   +1 more source

Sorption of alkylphenols and estrogens on microplastics in marine conditions

Open Chemistry, 2023
In marine ecosystems, living organisms are continuously exposed to a cocktail of anthropogenic contaminants, such as microplastics (MPs) and endocrine disrupting compounds (EDCs).
Phuong Ngoc Nam, Zalouk-Vergnoux Aurore, Duong Thi Thuy, Le Thi Phuong Quynh, Poirier Laurence   +4 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Manufacturing of nanopillar (ultra-dispersed) catalytically active materials through chemical engineering

Тонкие химические технологии, 2021
Objectives. Catalytically active materials are required in different chemical engineering processes. This makes the development of new materials with high efficiency and original ways in which to obtain them of significant interest.
A. P. Antropov, N. K. Zaytsev, Ye. D. Ryabkov, N. A. Yashtulov, P. N. Mudrakova   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Distance correlation coefficients for Lancaster distributions

Journal of Multivariate Analysis, 2017
We consider the problem of calculating distance correlation coefficients between random vectors whose joint distributions belong to the class of Lancaster distributions. We derive under mild convergence conditions a general series representation for the distance covariance for these distributions.
Johannes Dueck, Dominic Edelmann, Donald Richards   +2 more
openaire   +2 more sources

Separation of tungsten and rhenium on alumina [PDF]

Journal of the Serbian Chemical Society, 2004
The conditions for the efficient separation of tungsten(VI) and rhenium (VII) on alumina were established. The distribution coefficients Kd for tungstate and perrhenate anions, as well as the separation factors a (a = KdWO42-/Kd ReO4-) were determined ...
MILOVAN SM. STOILJKOVIC, DRAGOLJUB M. LUKIC, JURIJ L. VUCINA   +2 more
doaj   +3 more sources