Results 131 to 140 of about 3,055,792 (311)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Mesoscience has recently been proposed as a possible general concept for describing complex systems far from equilibrium, however, concrete formulations are needed, and particularly, a statistical mechanics foundation of mesoscience remains to be ...
Li, Jinghai +5 more
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Computing the Two-Sided Kolmogorov-Smirnov Distribution
We propose an algorithm to compute the cumulative distribution function of the two-sided Kolmogorov-Smirnov test statistic D_n and its complementary distribution in a fast and reliable way.
Pierre L'Ecuyer, Richard Simard
core
Quality of service is of major economic significance in natural monopoly infrastructure industries but is generally not reflected in efficiency analysis.
Growitsch, Christian +2 more
core +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On an analog of the M.G. Krein theorem for measurable operators
Let M be a von Neumann algebra of operators on a Hilbert space H and τ be a faithful normal semifinite trace on M. Let μt(T), t > 0, be a rearrangement of a τ-measurable operator T. Let us consider a τ-measurable operator A, such that μt(A) > 0 for all t
A.M. Bikchentaev
doaj

