Results 231 to 240 of about 8,449,255 (288)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

POMFinder: identifying polyoxometallate cluster structures from pair distribution function data using explainable machine learning. [PDF]

J Appl Crystallogr
Anker AS, Kjær ETS, Juelsholt M, Jensen KMØ.   +3 more
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Improved estimation of population distribution function using twofold auxiliary information under simple random sampling. [PDF]

Heliyon
Ahmad S, Hussain S, Al Mutairi A, Kamal M, Rehman MU, SidAhmed Mustafa M.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

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Functional Equations and Distribution Functions

Results in Mathematics, 1994
Let \(a \in (0,1)\), \(N \in \mathbb{N} \backslash \{1\}\) and \(- 1 = \beta_0 \leq \beta_1 \leq \dots \leq \beta_{N - 1} = 1\). Then the functional equation \[ f(x) = {1 \over N} \sum^{N - 1}_{k = 0} f \left( {x - \beta_k \over a} \right) \] has a unique bounded solution \(f : \mathbb{R} \to \mathbb{R}\) vanishing on \((- \infty, -1/(1 - a))\) and ...
Borwein, Jonathan M., Girgensohn, Roland
openaire   +1 more source

Molecular distribution functions

1974
Abstract In this chapter, we introduce the concepts of molecular distribution function (MDF), in one- and multicomponent systems. The MDFs are the fundamental ingredients in the modern molecular theories of liquids and liquid mixtures.
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Distribution Functions and Positive-Definite Functions

The Annals of Mathematics, 1934
The distribution of the values of a real almost periodic function or more generally of an almost periodic curve in several dimensions has been investigated lately by Wintner, Haviland and others.' One of the methods applied by Wintner depends on the use of Fourier transforms and is as such a standard method in the theory of probability.
Bochner, Salomon, Jessen, B.
openaire   +1 more source

Radial Patterson Distribution Functions

Nature, 1949
IT has been indicated in a previous paper1 how a comparison between the structure factors (F(h,k,l)) resulting from a given molecular configuration, and those actually observed by experiment, can be effected by comparing the Patterson maps resulting from the observations and from the proposed molecule.
ANDREW D. BOOTH, DOROTHY WRINCH
openaire   +1 more source