Results 41 to 50 of about 2,245,682 (297)

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Analysis of Type-II Censored Competing Risks’ Data under Reduced New Modified Weibull Distribution

Complexity, 2021
Models with the bathtub-shaped hazard rate function are widely used in lifetime analysis and reliability engineering. In this paper, we adopted the reduced new modified Weibull (RNMW) distribution with a bathtub-shaped hazard rate function.
Saad J. Almalki, Tahani A. Abushal, M. D. Alsulami, G. A. Abd-Elmougod   +3 more
doaj   +1 more source

Leptokurtic Portfolio Theory

, 2005
The question of optimal portfolio is addressed. The conventional Markowitz portfolio optimisation is discussed and the shortcomings due to non-Gaussian security returns are outlined. A method is proposed to minimise the likelihood of extreme non-Gaussian
Kalda, Jaan, Kitt, Robert
core   +3 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Social and Ethical Aspects [of Organic Food Provisioning] [PDF]

, 2005
This paper indicates the character of social and ethical concerns of consumers with respect to the production, distribution and marketing of organic food, discusses the extent to which these concerns can be addressed within the framework of risk analysis
Kjærnes, Unni, O'Doherty Jensen, Katherine, Torjusen, Hanne   +2 more
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Distribution of major health risks: findings from the Global Burden of Disease study.

PLoS Medicine, 2004
BackgroundMost analyses of risks to health focus on the total burden of their aggregate effects. The distribution of risk-factor-attributable disease burden, for example by age or exposure level, can inform the selection and targeting of specific ...
Anthony Rodgers, Majid Ezzati, Stephen Vander Hoorn, Alan D Lopez, Ruey-Bin Lin, Christopher J L Murray, Comparative Risk Assessment Collaborating Group   +6 more
doaj   +1 more source

A Process for Managing Risks in Distributed Teams [PDF]

IEEE Software, 2010
Today, many software projects are geographically distributed, so software managers must know how to manage distributed teams. For example, they need to know how to build teams across sites, how to break down and distribute tasks, how to share knowledge across time, space, and cultural differences, and how to coordinate work to produce coherent outcomes.
Persson, John Stouby; id_orcid 0000-0003-0422-1380, Mathiassen, Lars   +1 more
openaire   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Elevational Distribution and Extinction Risk in Birds [PDF]

PLOS ONE, 2015
Mountainous regions are hotspots of terrestrial biodiversity. Unlike islands, which have been the focus of extensive research on extinction dynamics, fewer studies have examined mountain ranges even though they face increasing threats from human pressures - notably habitat conversion and climate change.
White, Rachel, Bennett, Peter
openaire   +4 more sources