Results 101 to 110 of about 5,121,100 (298)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The impact of wakeup schedule distribution in synchronous power save protocols on the performance of multihop wireless networks [PDF]

open access: yes, 2007
By definition, the operation of an asynchronous power save protocol permits an arbitrary distribution of nodes' wakeup schedules. This wakeup schedule distribution creates an uncoordinated pattern of times at which nodes will attempt to transmit ...
Ahlgren, Bengt   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A geochemical drainage survey of the Fleet granitic complex and its environs [PDF]

open access: yes, 1978
A regional geochemical drainage reconnaissance programme was undertaken over 900 km2 of south-west Scotland centred on the Fleet granitic complex. Rocks of Ordovician and Silurian age outcrop over the area, into which have been intruded the Fleet and ...
Brown, M.J.   +3 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Cross Sectional Evolution of the US City Size Distribution [PDF]

open access: yes
We report nonparametrically estimated stochastic transition kernels for the evolution of the distribution of US metropolitan area populations, for the period 1900 to 1990.
Henry Overman, Y Ioannides
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Análise da distribuição volumétrica de pontas de pulverização hidráulicas de jato plano Volumetric distribution analysis of flat fan hydraulic spray nozzles

open access: yesRevista de Ciências Agrárias, 2008
O padrão de deposição volumétrica é um parâmetro muito importante para a seleção da ponta de pulverização adequada para cada aplicação de agrotóxico. Assim, este trabalho teve como objetivo analisar a distribuição volumétrica de pontas de pulverização ...
João Paulo Arantes Rodrigues da Cunha
doaj  

National and international income dispersion and aggregate expenditures [PDF]

open access: yes
We examine linkages between aggregate household income, distribution of that income, and aggregate cross-country expenditure patterns. We are able to decompose income effects into international income dispersion effects (from variations in average income)
Carmen Fillat, Joseph Francois
core  

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