Results 41 to 50 of about 7,437 (308)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Voltage Support Provided by STATCOM in Unbalanced Power Systems

Energies, 2014
The presence of an unbalanced voltage at the point of common coupling (PCC) results in the appearance of a negative sequence current component that deteriorates the control performance.
Ana Rodríguez, Emilio J. Bueno, Álvar Mayor, Francisco J. Rodríguez, Aurelio García-Cerrada   +4 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Optimal Integration of D-STATCOMs in Radial and Meshed Distribution Networks Using a MATLAB-GAMS Interface

Algorithms, 2023
This paper proposes an interconnection of the MATLAB and GAMS software interfaces, which were designed based on a master-slave methodology, to solve the mixed-integer nonlinear programming (MINLP) model problem associated with the problem regarding the ...
German Francisco Barreto-Parra, Brandon Cortés-Caicedo, Oscar Danilo Montoya   +2 more
doaj   +1 more source

Design and Realization of Distribution Static Synchronous Compensator

Advances in Engineering Research, 2014
According to the engineering requirement of power distribution network reactive power compensation, the paper presents a software and hardware design method of the STATCOM based on DSP. In order to stabilize the PCC voltage around a prescribed value in the direct current control mode, the three-level converter of three phase bridge of the equipment in ...
Feng Chen, Linsuo Zeng
openaire   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Analysis of Pre- and during COVID-19 Mixed Load Models on Unbalanced Radial Distribution System Using a New Metaphor-Less Rao Optimization

International Transactions on Electrical Energy Systems, 2023
An unbalanced electrical distribution system (DS) with radial construction and passive nature suffers from significant power loss. The unstable load demand and poor voltage profile resulted from insufficient reactive power in the DS.
Jitendra Singh Bhadoriya, A. R. Gupta, Baseem Khan   +2 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Unstationnary control of a launcher using observer-based structures [PDF]

, 2003
This paper deals with the design of a gain-scheduled controller for the attitude control of a launcher during atmospheric flight. The design is characterized by classical requirements such as phase/gain margins and flexible mode attenuations as well as
Alazard, Daniel, Clément, Benoît, Voinot, Olivier   +2 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source