Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Investigating the impact of electric vehicles on increasing the reliability of the distribution system using the enhanced gray wolf evolutionary algorithm model. [PDF]
Naeimi M +4 more
europepmc +1 more source
Functional Distribution, Capital Accumulation and Growth in a Non-Linear Macrodynamic Model
The article develops a macrodynamic model of income distribution, capital accumulation, and growth in which investment is nonlinear in distribution: at intermediate and high (low) levels of wage share, the impact of a higher profit share on investment ...
Lima, Gilberto Tadeu
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Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Control of Brominated and Iodinated DBPs within a Drinking Water Distribution System with Granular Activated Carbon and Biological Filtration. [PDF]
Kajjumba GW +10 more
europepmc +1 more source
The mode-based decomposition into the growth and distribution effects for segments of poor
This study proposes the mode-based decomposition approach to better examine the change of the wealth of more impoverished populations into growth and distribution effects.
Yamada, Takahiro
core
State of Ohio : strategic plan
Title from URL of PDF document (viewed Nov. 1, 2005).; "6/20/2005"--P. 1, etc.; Harvested from the web on 11/1/055.3.1.00 general ledger (135 p.) -- 5.3.2.00 accounts payable (77 p.) -- 5.3.3.00 procurement (180 p.) -- 5.3.4.00 grants, project costing ...
Ohio Administrative Knowledge System.
core
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Network reconfiguration and DG based compensation of Wolaita Sodo distribution system by using particle swarm optimisation. [PDF]
Alemayehu B +3 more
europepmc +1 more source
Cambridge Distribution in a World Economy
The article outlines a two-country Cambridge model of growth and distribution. The condition for the Cambridge equation to apply to the world economy is outlined.
O’Connell, Joan
core

