Results 261 to 270 of about 2,335,988 (318)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Integrating Distributed Algorithms into Distributed Systems [PDF]

open access: possibleFundamenta Informaticae, 1999
A distributed algorithm is often used as a part of a larger distributed system. Usually, the properties of an algorithm are proven for the algorithm in isolation. Then, it is not obvious how the algorithm behaves when integrated into a larger system. In this paper, we present a simple technique which allows to derive properties of an algorithm which is
Ekkart Kindler, Sibylle Peuker
openaire   +2 more sources

Distributed Systems

Computer, 1985
Growth of distributed systems has attained unstoppable momentum. If we better understood how to think about, analyze, and design distributed systems, we could direct their implementation with more confidence.
openaire   +1 more source

On a System of Discrete Distributions

Biometrika, 1967
Using the difference equation analogous to Pearson's differential equation, a system of discreate distributions is developed. This is found to contain many of the distributions in common usage. The choice of distribution usually depends on only the first three moments. Some examples are given.
openaire   +3 more sources

Dissipative distributed systems

Proceedings of the 39th IEEE Conference on Decision and Control (Cat. No.00CH37187), 2002
Deals with systems described by constant coefficient linear partial differential equations. We define dissipativity with respect to a quadratic differential form, i.e., a quadratic functional in the system variables and their partial derivatives. The main result states the equivalence of dissipativity and the existence of a storage function or of a ...
Harish K. Pillai, Jan C. Willems
openaire   +1 more source

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